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Which layer of the cornea is the thickest?

  1. Endothelium

  2. Stroma

  3. Epithelium

  4. Descemet's membrane

The correct answer is: Stroma

The stroma is indeed the thickest layer of the cornea. Comprising approximately 90% of the corneal thickness, the stroma is made up of organized collagen fibers and keratocytes, which provide the cornea with its strength and transparency. This layer plays a crucial role in maintaining corneal shape and integrity, contributing to the overall function of the eye by supporting refraction. The endothelium, while essential for maintaining proper hydration of the cornea and thus its transparency, is much thinner compared to the stroma. The epithelium, the outermost layer, serves as a protective barrier against environmental insults, but it is also thinner than the stroma. Descemet's membrane, a thin, elastic layer located just beneath the endothelium, is also considerably thinner than the stroma. Each of these other layers plays important roles in corneal function, but the stroma stands out as the thickest, vital for the overall stability and health of the corneal structure.