Certified Ophthalmic Assistant Practice Exam

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Which medication is known for lowering aqueous humor production to manage glaucoma?

  1. Timolol maleate

  2. Brimonidine

  3. Bimatoprost

  4. Latanoprost

The correct answer is: Timolol maleate

Timolol maleate is a non-selective beta-blocker that is widely used in the management of glaucoma. It works by reducing the production of aqueous humor, which helps to lower intraocular pressure in patients with glaucoma. By decreasing the fluid produced, timolol effectively helps to prevent damage to the optic nerve that can occur with elevated pressure. Brimonidine, while it also helps manage glaucoma, primarily acts by increasing uveoscleral outflow and has some additional effects on reducing aqueous humor production. However, its main mechanism differs from that of timolol. Bimatoprost and latanoprost are prostaglandin analogs that mainly work by increasing the outflow of aqueous humor. They do not significantly lower production; rather, they enhance the drainage of fluid from the eye, which also contributes to lowering intraocular pressure. Thus, timolol maleate is specifically recognized for its role in decreasing aqueous humor production, making it the correct response for managing glaucoma in this context.

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